Professor of Medical Genetics
University of Turin
Turin, Italy
Silvia Deaglio, MD, PhD is Full Professor of Genetics at the University of Turin, where she works in the Transplant Immunogenetic Service of the local University Hospital.
In 2004-2005, during her PhD, she trained at the Transplant Immunology Unit of the Beth Israel Deaconess Medical Center of Harvard University, where she contributed to the identification of molecular components and genetic regulation of the suppressive machinery of regulatory T cells. After going back to Italy at the end of 2005, she established her own laboratory, focused on the genetic characterization of tumor-host interactions, particularly using chronic lymphocytic leukemia as a model. Her lab contributed to the identification and functional characterization of recurrently mutated genes in CLL. From 2014 to 2016, she was visiting associate professor at Weill Cornell Medical College, to set up patient-derived xenograft models of CLL and Richter syndrome. These models are being extensively used to study disease mechanisms and therapy responses.
Session 3: Microenvironment and Pre-Clinical Immunotherapies
Saturday, October 7, 2023
1:55 PM – 3:25 PM EDT
In Vivo Modeling of CLL Transformation: PDX Model
Monday, October 9, 2023
8:15 AM – 8:25 AM EDT
Panel Discussion on In Vivo Modeling
Monday, October 9, 2023
8:45 AM – 8:55 AM EDT