Session 3: Microenvironment and Pre-Clinical Immunotherapies

Co-Chair(s)

• 

  Adrian Wiestner, MD, PhD

  Senior Investigator
  Laboratory of Lymphoid Malignancies, National Heart, Lung, and Blood Institute, National Institutes of Health
  Bethesda, MD, United States
• 

  Silvia Deaglio, MD, PhD

  Professor of Medical Genetics
  University of Turin
  Turin, Italy

Presentations:

• 1:55 PM – 2:10 PM EDT

  Anti-Tumor Immunity in the Lymphoid Microenvironment
  

  Speaker: Martina Seiffert, PhD – German Cancer Research Center
• 2:10 PM – 2:25 PM EDT

  The Tumor Supportive Microenvironment of CLL
  

  Speaker: Jerome Paggetti, PhD – Luxembourg Institute of Health
• 2:25 PM – 2:35 PM EDT

  Modeling the Tumor Microenvironment of CLL In Vitro
  

  Speaker: Cristina Scielzo, PhD – IRCCS, Hospital San Raffaele
• 2:35 PM – 2:45 PM EDT

  The Tumor Microenvironment and Genetic Heterogeneity of CLL
  

  Speaker: Clare Sun, MD – Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health
• 2:45 PM – 3:05 PM EDT

  Panel Discussion With Interactivity and Audience Q&A
• 3:05 PM – 3:15 PM EDT

  Constituitive VLA-4 activation is linked to BCR autonomous signaling in circulating CLL cells and promotes pro-survival signals through soluble blood-borne VCAM-1 binding
  

  Primary Author; Presenting Author: Erika Tissino, PhD – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS

  Co-Author: Riccardo Bomben, Dr – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS

  Co-Author: Palash C. Maity, PhD – Universitätsklinikum Ulm

  Co-Author: Federico Pozzo, PhD – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS

  Co-Author: Antonella Nicolò, PhD – Universitätsklinikum Ulm

  Co-Author: Annalisa Gaglio, Dr – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS

  Co-Author: Tamara Bittolo, PhD – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS

  Co-Author: Francesca M. Rossi, Dr – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS

  Co-Author: Moumita Datta, PhD – Universitätsklinikum Ulm

  Co-Author: Francesco Zaja, Dr – Department of Medical, Surgical and Health Sciences, University of Trieste

  Co-Author: Giovanni D'Arena, Dr – IRCCS Centro Di Riferimento Oncologico Della Basilicata

  Co-Author: Annalisa Chiarenza, Dr – Division of Hematology, Policlinico, Department of Surgery and Medical Specialties, University of Catania

  Co-Author: Hassan Jumaa, Professor – Universitätsklinikum Ulm

  Co-Author: Maria Ilaria del Principe, MD – Università degli studi di Roma Tor Vergata

  Co-Author: Roberta Laureana, MD – Division of Haematology, University of Tor Vergata

  Co-Author: Jacopo Olivieri, MD – Clinica Ematologia di Udine

  Co-Author: Tanja Hartmann, Professor – University of Freiburg

  Co-Author: Valter Gattei, Professor – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS

  Co-Author: Antonella Zucchetto, PhD – Centro di Riferimento Oncologico di Aviano (CRO) IRCCS
• 3:15 PM – 3:25 PM EDT

  Exploiting the modulation of FOXO1 signalling as a therapeutic target in CLL through combination of ERK and BTK inhibition
  

  Primary Author; Presenting Author: Jodie F. Hay, PhD – University of Glasgow

  Co-Author: Alison M. Michie, PhD – University of Glasgow