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Adrian Wiestner, MD, PhD

Senior Investigator
Laboratory of Lymphoid Malignancies, National Heart, Lung, and Blood Institute, National Institutes of Health
Bethesda, MD, United States

Dr. Adrian Wiestner leads the Laboratory of Lymphoid Malignancies, Hematology Branch, National Heart, Lung, and Blood Institute, NIH. Dr. Wiestner earned his M.D. from the University of Basel Medical School in Switzerland in 1992, and a Ph.D. in genetics in 1998. He joined the NIH with the NHLBI Hematology Fellowship Program in 2000. In September 2004, Dr. Wiestner was appointed as a Tenure Track Investigator with the NHLBI Hematology Branch and was promoted to Senior Investigator in December 2013. As senior investigator on clinical trials and principal investigator of the laboratory program, I combine clinical and laboratory investigation that aim to improve treatment for patients with B-cell malignancies, in particular Chronic Lymphocytic Leukemia (CLL). I am pursuing three major goals: First, identify pathogenic mechanisms to assist the development of targeted therapy. Second, evaluate novel agents and treatment concepts in clinical trials. Third, investigate resistance mechanisms through pharmacodynamic and genetic studies in patients enrolled on our clinical trials.

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