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Catherine J. Wu, MD

Professor of Medicine and Chief, Division of Stem Cell Transplantation and Cellular Therapies
Dana-Farber Cancer Institute, Harvard Medical School
Boston, MA, United States

Catherine J. Wu, MD is a Professor of Medicine and Chief, Division of Stem Cell Transplantation and Cellular Therapies and the Lavine Family Chair for Preventative Care Therapies at the Dana-Farber Cancer Institute, Boston. She is a member of the National Academy of Medicine and the Association of American Physicians. She received her M.D. from Stanford University School of Medicine and completed her clinical training in Internal Medicine and Hematology-Oncology at the Brigham and Women’s Hospital and Dana-Farber Cancer Institute in Boston, MA. She joined the staff at the Dana-Farber Cancer Institute in 2000. Her research program at DFCI has consistently focused on addressing a fundamental feature of cancer: its genomic heterogeneity—providing a means to evolve, adapt and escape from immune control. At the same time, she has studied the adaptive immune system, which is inherently engineered to be exquisitely responsive to environmental challenges, possessing fundamental ‘search and destroy’ functions and the capacity to provide long-term protective immunologic memory, of cancer patients. Her central focus has been thus to understand the molecular basis of tumor-host coevolution, both with natural cancer progression and with therapeutic perturbation. These have been primarily genomics based studies to systematically analyze model systems and human specimens, conducted most extensively in blood malignancies such as chronic lymphocytic leukemia (CLL).

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