Session 1: Integrative Aspects of Genomics

Co-Chair(s)

• 

  Gad Getz, PhD

  Professor of Pathology
  The Broad Institute of MIT and Harvard
  Boston, MA, United States
• 

  Christopher Oakes, PhD

  Associate Professor, Departments of Internal Medicine and Biomedical Informatics
  The Ohio State University
  Columbus, OH, United States

Presentations:

• 8:40 AM – 8:55 AM EDT

  Multiomic Integration in CLL
  

  Speaker: Cynthia K. Hahn, MD, PhD – Dana-Farber Cancer Institute
• 8:55 AM – 9:10 AM EDT

  Whole-Genome Analysis of CLL and Interplay of Coding, Non-Coding, Transcriptome and Epigenetic Events
  

  Speaker: Pauline Robbe, D.Phil (Oncology) – RIKEN Center for Integrative Medical Sciences
• 9:10 AM – 9:20 AM EDT

  Genomics of Richter's Transformation: Part I
  

  Speaker: Ferran Nadeu, PhD – Fundació de Recerca Clínic Barcelona - Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)
• 9:20 AM – 9:30 AM EDT

  Genomics of Richter's Transformation: Part II
  

  Speaker: Erin M. Parry, MD, PhD – Dana-Farber Cancer Institute
• 9:30 AM – 9:40 AM EDT

  Commentary on Each Other's Work and Consensus Regarding the Genomics of Richter's Transformation
  

  Speaker: Ferran Nadeu, PhD – Fundació de Recerca Clínic Barcelona - Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS)

  Speaker: Erin M. Parry, MD, PhD – Dana-Farber Cancer Institute
• 9:40 AM – 9:50 AM EDT

  Panel Discussion With Interactivity and Audience Q&A
• 9:50 AM – 10:00 AM EDT

  SF3B1 mutation and ATM deletion co-drive leukemogenesis via centromeric R-loop dysregulation
  

  Primary Author: Martina Cusan, PhD – Department of Systems Biology, Beckman Research Institute of the City of Hope

  Co-Author: Haifeng Shen, PhD – Department of Systems Biology, Beckman Research Institute of the City of Hope

  Co-Author: Lu Yang – Department of Systems Biology, Beckman Research Institute of the City of Hope

  Co-Author: Meiling Jin, PhD – Department of Systems Biology, Beckman Research Institute, City of Hope National Comprehensive Cancer Center

  Co-Author: Mike Fernandez, BS – Department of Systems Biology, Beckman Research Institute of the City of Hope

  Co-Author: Prajish S. Iyer, PhD – Department of Systems Biology, Beckman Research Institute, City of Hope National Comprehensive Cancer Center

  Co-Author: Yiming Wu, PhD – Department of Systems Biology, Beckman Research Institute, City of Hope National Comprehensive Cancer Center

  Co-Author: Catherine Gutierrez, MD, PhD – Department of Medical Oncology, Dana-Farber Cancer Institute

  Co-Author: Catherine J. Wu, MD – Dana-Farber Cancer Institute, Harvard Medical School

  Co-Author: Renjang Lin, PhD – Center for RNA Biology and Therapeutics, Beckman Research Institute of the City of Hope

  Co-Author; Presenting Author: Lili Wang, MD, PhD – Beckman Research Institute, City of Hope National Comprehensive Cancer Center, Monrovia; Toni Stephenson Lymphoma Center, Beckman Research Institute, City of Hope Comprehensive Cancer Center
• 10:00 AM – 10:10 AM EDT

  Oncogenic role and target properties of the lysine-specific demethylase KDM1A in chronic lymphocytic leukemia
  

  Primary Author; Presenting Author: Qu Jiang, PhD – Department for Hematology, Cell Therapy and Hemostaseology, University Hospital of Leipzig

  Co-Author: Johanna Stachelscheid, PhD – Cologne Excellence Cluster on Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne

  Co-Author: Johannes Bloehdorn, MD – Department III of Internal Medicine, Ulm University

  Co-Author: Alicja Pacholewska, PhD – Institute for Translational Epigenetics, Faculty of Medicine, University Hospital Cologne, University of Cologne

  Co-Author: Stephan Stilgenbauer, MD, PhD – Department of Internal Medicine III, Ulm University

  Co-Author: Michael Hallek, MD – Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne

  Co-Author: Michal R. Schweiger, PhD – Institute for Translational Epigenetics, Faculty of Medicine, University Hospital Cologne, University of Cologne

  Co-Author: Elena Vasyutina, PhD – University Hospital of Cologne

  Co-Author: Marco Herling, MD – Department for Hematology, Cell Therapy and Hemostaseology, University Hospital of Leipzig